ZNF714

Across TCGA cell cohorts, ZNF714 mutation is significantly associated with the drug of many other genes, with 26 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF714-associated genes across cancer lineages are Ispinesib Mesylate, WYE-125132, and AST-1306. Each is linked with ZNF714 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF714-to-partner and partner-to-ZNF714 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ispinesib Mesylate grouped by ZNF714-low versus ZNF714-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF714→partner) and Y-score (partner→ZNF714) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Ispinesib Mesylate →	+0.648	+2.652	.048	.045	3	1
LARGE_INTESTINE	WYE-125132 →	+0.694	+2.652	.005	.045	3	1
LARGE_INTESTINE	AST-1306 →	+0.627	+2.684	.004	.035	3	1
LARGE_INTESTINE	CD532 →	+0.461	+2.652	.021	.045	3	1
LARGE_INTESTINE	CP466722 →	+0.422	+2.652	.033	.045	2	1
LARGE_INTESTINE	SGC-CBP30 →	+0.317	+2.649	.024	.046	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

Ispinesib Mesylate by ZNF714 expression — LARGE_INTESTINE

Explore this box plot interactively →