ZNF711

Across TCGA patient cohorts, ZNF711 mutation is significantly associated with the RNA expression of many other genes, with 5,000 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF711-associated genes across cancer lineages are ZWINT, CENPK, and HROB. Each is linked with ZNF711 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF711-to-partner and partner-to-ZNF711 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZWINT grouped by ZNF711-low versus ZNF711-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF711→partner) and Y-score (partner→ZNF711) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ZWINT →	+0.700	+3.000	<.001	<.001	3	4
UCEC	CENPK →	+0.622	+2.131	<.001	<.001	3	3
UCEC	HROB →	+0.470	+1.606	<.001	<.001	3	3
UCEC	AUNIP →	+0.553	+1.765	<.001	<.001	3	3
UCEC	SMC2 →	+0.703	+1.786	<.001	<.001	3	3
UCEC	NUSAP1 →	+0.764	+2.169	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,000 associations by consensus.

ZWINT by ZNF711 expression — UCEC

Explore this box plot interactively →