ZNF710

Across TCGA patient cohorts, ZNF710 mutation is significantly associated with the RNA expression of many other genes, with 1,298 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF710-associated genes across cancer lineages are NDUFC1, PLPP3, and UQCRH. Each is linked with ZNF710 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF710-to-partner and partner-to-ZNF710 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NDUFC1 grouped by ZNF710-low versus ZNF710-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF710→partner) and Y-score (partner→ZNF710) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NDUFC1 →	+0.339	+1.947	.006	.003	3	3
UCEC	PLPP3 →	-0.720	-2.305	.009	.006	3	3
UCEC	UQCRH →	+0.732	+3.732	.009	<.001	3	3
UCEC	RNA5SP86 →	+0.299	+2.373	<.001	.004	3	3
BRCA	NUTF2P8 →	+0.072	+4.431	.003	.008	3	2
HNSC	SRSF1P1 →	+0.215	+5.578	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,298 associations by consensus.

NDUFC1 by ZNF710 expression — UCEC

Explore this box plot interactively →