ZNF710

Across TCGA patient cohorts, ZNF710 mutation is significantly associated with the total protein of many other genes, with 30 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF710-associated genes across cancer lineages are GAPDH, MEK1, and PKC-a. Each is linked with ZNF710 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF710-to-partner and partner-to-ZNF710 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAPDH grouped by ZNF710-low versus ZNF710-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF710→partner) and Y-score (partner→ZNF710) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GAPDH →	+0.514	+3.321	.017	.009	3	2
UCEC	MEK1 →	+0.440	+3.321	.002	.009	3	2
UCEC	PKC-a →	-0.405	-2.584	.012	.010	3	2
UCEC	PTEN →	-0.460	-3.169	.004	.018	3	2
UCEC	Rad50 →	-0.226	-1.906	.020	.016	3	2
UCEC	Src_pY527 →	-0.395	-1.990	.022	.030	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

GAPDH by ZNF710 expression — UCEC

Explore this box plot interactively →