ZNF710

Across TCGA cell cohorts, ZNF710 mutation is significantly associated with the RNA expression of many other genes, with 31 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF710-associated genes across cancer lineages are TFDP3, KRT6C, and GALP. Each is linked with ZNF710 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF710-to-partner and partner-to-ZNF710 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TFDP3 grouped by ZNF710-low versus ZNF710-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF710→partner) and Y-score (partner→ZNF710) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TFDP3 →	+0.031	+4.196	<.001	.002	3	2
BLOOD_Leukemia	KRT6C →	+0.021	+4.037	<.001	.004	3	2
LUNG_NSCLC_LUSC	GALP →	+0.040	+4.643	<.001	.008	3	1
LUNG_NSCLC_LUSC	MINDY4B →	+0.060	+4.643	<.001	.008	3	1
LUNG_NSCLC_LUSC	MROH5 →	+0.070	+4.643	.001	.008	3	1
LARGE_INTESTINE	CSN2 →	+0.031	+3.684	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

TFDP3 by ZNF710 expression — LARGE_INTESTINE

Explore this box plot interactively →