ZNF707

Across TCGA cell cohorts, ZNF707 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF707-associated genes across cancer lineages are TIFAB, VSX2, and DNAI1. Each is linked with ZNF707 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF707-to-partner and partner-to-ZNF707 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TIFAB grouped by ZNF707-low versus ZNF707-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF707→partner) and Y-score (partner→ZNF707) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TIFAB →	+0.006	+4.977	<.001	.007	3	1
BLOOD_Leukemia	VSX2 →	+0.023	+3.966	<.001	<.001	3	1
BLOOD_Leukemia	DNAI1 →	+0.160	+3.257	<.001	.009	3	1
BLOOD_Leukemia	GSC →	+0.668	+3.211	.007	.002	3	1
BLOOD_Leukemia	NPFFR1 →	+0.008	+2.774	.005	.006	3	1
BLOOD_Leukemia	LGI3 →	+0.195	+2.754	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

TIFAB by ZNF707 expression — LARGE_INTESTINE

Explore this box plot interactively →