ZNF706

Across TCGA patient cohorts, ZNF706 mutation is significantly associated with the RNA expression of many other genes, with 58 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF706-associated genes across cancer lineages are PMS2P6, NUDT4B, and MIR3193. Each is linked with ZNF706 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF706-to-partner and partner-to-ZNF706 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PMS2P6 grouped by ZNF706-low versus ZNF706-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF706→partner) and Y-score (partner→ZNF706) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PMS2P6 →	+0.366	+3.081	<.001	.005	3	1
UCEC	NUDT4B →	+0.080	+3.884	<.001	.002	3	1
UCEC	MIR3193 →	+1.032	+3.575	<.001	.001	3	1
UCEC	MIR4710 →	+0.691	+3.294	<.001	.007	3	1
UCEC	EML2-AS1 →	+0.109	+3.177	<.001	.003	3	1
UCEC	MIA-RAB4B →	+0.126	+4.670	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 58 associations by consensus.

PMS2P6 by ZNF706 expression — UCEC

Explore this box plot interactively →