ZNF706

Across TCGA cell cohorts, ZNF706 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF706-associated genes across cancer lineages are OR1L6, CROCC2, and C17orf98. Each is linked with ZNF706 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF706-to-partner and partner-to-ZNF706 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR1L6 grouped by ZNF706-low versus ZNF706-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF706→partner) and Y-score (partner→ZNF706) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR1L6 →	+0.022	+4.437	<.001	.004	3	1
LARGE_INTESTINE	CROCC2 →	+0.108	+3.793	.008	.007	3	1
LARGE_INTESTINE	C17orf98 →	+0.086	+3.793	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

OR1L6 by ZNF706 expression — LARGE_INTESTINE

Explore this box plot interactively →