Across TCGA pan-cancer cohorts, ZNF705D RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of ZNF705D’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where ZNF705D RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ZNF705D is over-expressed in tumor.
KIRC and LUAD are the cancer types where ZNF705D tumor–normal differential expression is most reproducible.