Across TCGA patient cohorts, ZNF705A mutation is significantly associated with the total protein of many other genes, with 45 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF705A-associated genes across cancer lineages are FoxM1, INPP4B, and mTOR_pS2448. Each is linked with ZNF705A in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF705A-to-partner and partner-to-ZNF705A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF705A→partner) and Y-score (partner→ZNF705A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FoxM1 →	+0.245	+1.847	.009	.008	3	2
UCEC	INPP4B →	-0.304	-2.807	.010	.002	3	2
UCEC	mTOR_pS2448 →	-0.133	-1.980	.015	.030	3	2
UCEC	Cyclin-B1 →	+0.734	+3.584	<.001	.002	3	2
SKCM	PDK1_pS241 →	-0.191	-2.304	.020	.035	3	2
UCEC	14-3-3_beta →	-0.101	-2.432	.006	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 45 associations by consensus.

Exploration

ZNF705A survival (RNA) · tumor vs normal (RNA) · all ZNF705A data types