ZNF7

Across TCGA pan-cancer cohorts, ZNF7 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ZNF7 data layer compared with 21 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher ZNF7 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated ZNF7 expression acts as an unfavorable survival marker, although some lineages such as UCEC and LSCC show a favorable association.

GBM, HNSC, and UCEC are the cancer types where ZNF7 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	OS	Quartile	All	0.308	0.908	.002	22	view →
HNSC	DFS	Tertile	III,IV	0.574	1.000	.022	6	view →
UCEC	DFS	Tertile	All	1.000	0.728	.020	4	view →
PDAC	DFS	Median	All	0.203	0.647	.038	3	view →
LSCC	DFS	Median	II,III,IV	1.000	0.878	.035	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

ZNF7–GBM (OS)

Open the GBM breakdown →