Across TCGA pan-cancer cohorts, ZNF696 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated ZNF696 data layer compared with 23 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher ZNF696 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated ZNF696 expression acts as an unfavorable survival marker, although some lineages such as GBM and LSCC show a favorable association.

GBM, LUAD, and LSCC are the cancer types where ZNF696 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	OS	Quartile	All	0.892	0.384	.006	12	view →
LUAD	DFS	Median	II,III,IV	0.193	0.807	.022	7	view →
LSCC	DFS	Tertile	All	0.850	0.458	.046	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: ZNF696 tumor-vs-normal RNA expression · all ZNF696 data types