Across TCGA patient cohorts, ZNF696 mutation is significantly associated with the RNA expression of many other genes, with 656 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF696-associated genes across cancer lineages are DEFB4B, OR6K2, and RBMY1HP. Each is linked with ZNF696 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF696-to-partner and partner-to-ZNF696 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF696→partner) and Y-score (partner→ZNF696) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	DEFB4B →	+0.777	+4.169	<.001	.008	3	1
SCLC	OR6K2 →	+0.067	+4.624	<.001	.006	3	1
HNSC	RBMY1HP →	+0.024	+7.954	<.001	.008	3	1
HNSC	RNU6-1325P →	+0.338	+7.954	<.001	.008	3	1
SKCM	OR51G1 →	+0.044	+7.816	<.001	.008	3	1
COAD	DDX53 →	+0.781	+4.354	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 656 associations by consensus.

Exploration

ZNF696 survival (RNA) · tumor vs normal (RNA) · all ZNF696 data types