Across TCGA patient cohorts, ZNF696 mutation is significantly associated with the total protein of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF696-associated genes across cancer lineages are FOXO3a_pS318_S321, ACC1, and Notch1. Each is linked with ZNF696 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF696-to-partner and partner-to-ZNF696 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF696→partner) and Y-score (partner→ZNF696) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FOXO3a_pS318_S321 →	-0.120	-2.999	.039	.035	3	1
UCEC	ACC1 →	+0.344	+3.013	.042	.018	3	1
UCEC	Notch1 →	+0.172	+2.820	.008	.035	3	1
UCEC	PKC-a_pS657 →	+0.426	+2.598	.016	.006	3	1
UCEC	4E-BP1 →	+0.261	+2.584	.039	.011	3	1
UCEC	Collagen-VI →	-0.246	-3.308	.010	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

ZNF696 survival (RNA) · tumor vs normal (RNA) · all ZNF696 data types