ZNF692

Across TCGA patient cohorts, ZNF692 mutation is significantly associated with the RNA expression of many other genes, with 2,423 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF692-associated genes across cancer lineages are EI24, SLC7A11, and BAG3. Each is linked with ZNF692 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF692-to-partner and partner-to-ZNF692 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EI24 grouped by ZNF692-low versus ZNF692-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF692→partner) and Y-score (partner→ZNF692) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EI24 →	+0.418	+2.628	.003	.005	3	2
UCEC	SLC7A11 →	+0.883	+2.917	<.001	<.001	3	2
UCEC	BAG3 →	+0.632	+3.871	<.001	<.001	3	2
UCEC	ATP5F1A →	+0.408	+2.470	.004	<.001	3	2
UCEC	FAM151B →	+0.233	+1.978	.009	.008	3	2
UCEC	NUS1 →	+0.466	+2.243	.002	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,423 associations by consensus.

EI24 by ZNF692 expression — UCEC

Explore this box plot interactively →