Across TCGA pan-cancer cohorts, ZNF69 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated ZNF69 data layer compared with 26 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher ZNF69 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ZNF69 expression acts as an unfavorable survival marker.

UCEC, CHOL, and CESC are the cancer types where ZNF69 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	All	0.765	0.927	.014	6	view →
CHOL	OS	Median	All	0.155	0.725	.029	3	view →
CESC	OS	Median	All	0.503	0.877	.019	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: ZNF69 tumor-vs-normal RNA expression · all ZNF69 data types