ZNF689

Across TCGA pan-cancer cohorts, ZNF689 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated ZNF689 data layer compared with 23 for mass-spec protein and 1 for mass-spec protein.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher ZNF689 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ZNF689 expression acts as an unfavorable survival marker.

ESCA are the cancer types where ZNF689 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Median	II,III,IV	0.216	0.702	.014	6	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

ZNF689–ESCA (OS)

Open the ESCA breakdown →