ZNF689

Across TCGA patient cohorts, ZNF689 RNA expression is significantly associated with the RNA expression of many other genes, with 20,128 significant associations in total. ACC shows the largest number of these associations.

The most reproducible ZNF689-associated genes across cancer lineages are EMSY, CCDC117, and NSD1. Each is linked with ZNF689 in more than 33 cancer types. Because this analysis shows association rather than direction, both ZNF689-to-partner and partner-to-ZNF689 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF689 versus EMSY in DLBC, with a Pearson correlation of 0.82.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF689→partner) and Y-score (partner→ZNF689) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	EMSY →	+1.052	+0.753	<.001	<.001	3	34
DLBC	CCDC117 →	+1.470	+0.711	<.001	<.001	3	34
DLBC	NSD1 →	+1.260	+0.685	<.001	<.001	3	34
DLBC	ZNF319 →	+1.012	+0.702	<.001	<.001	3	34
DLBC	ZBTB39 →	+1.341	+0.716	<.001	<.001	3	34
ACC	ZNF646 →	+1.073	+0.880	<.001	<.001	3	34

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,128 associations by consensus.

ZNF689 vs EMSY — DLBC

Explore this scatter interactively →