ZNF689

Across TCGA patient cohorts, ZNF689 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,837 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF689-associated proteins across cancer lineages are SAFB2, UBR7, and VEZF1. Each is linked with ZNF689 in more than 5 cancer types. Because this analysis shows association rather than direction, both ZNF689-to-partner and partner-to-ZNF689 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF689 versus SAFB2 in GBM, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF689→partner) and Y-score (partner→ZNF689) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SAFB2 →	+0.386	+0.322	<.001	<.001	3	5
BRCA	UBR7 →	+0.361	+0.937	.001	<.001	2	6
HNSC	VEZF1 →	+0.517	+0.690	<.001	<.001	3	5
GBM	ZMYM3 →	+0.416	+0.396	<.001	<.001	3	5
OV	CD2BP2 →	+0.515	+0.450	<.001	<.001	3	5
BRCA	TBC1D10B →	+0.274	+0.859	.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,837 associations by consensus.

ZNF689 vs SAFB2 — GBM

Explore this scatter interactively →