ZNF689

Across TCGA patient cohorts, ZNF689 protein abundance is significantly associated with the protein abundance of many other proteins, with 642 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible ZNF689-associated proteins across cancer lineages are CCT5, CLIP1_S204, and FES_T421. Each is linked with ZNF689 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF689-to-partner and partner-to-ZNF689 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF689 versus CCT5 in PDAC, with a Pearson correlation of -0.84.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF689→partner) and Y-score (partner→ZNF689) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	CCT5 →	-0.400	-0.625	.002	.001	3	1
PDAC	CLIP1_S204 →	-0.758	-0.503	<.001	<.001	3	1
PDAC	FES_T421 →	+0.868	+0.527	<.001	.006	3	1
PDAC	GFPT2_T227 →	+0.923	+0.456	<.001	.001	3	1
HNSC	C6orf132_S558 →	-0.491	-0.454	.002	.001	3	1
HNSC	CRYBG2_S224 →	-0.542	-0.644	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 642 associations by consensus.

ZNF689 vs CCT5 — PDAC

Explore this scatter interactively →