ZNF688

Across TCGA patient cohorts, ZNF688 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,934 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ZNF688-associated proteins across cancer lineages are TTC8, PDK1, and RPL3. Each is linked with ZNF688 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF688-to-partner and partner-to-ZNF688 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF688 versus TTC8 in BRCA, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF688→partner) and Y-score (partner→ZNF688) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TTC8 →	+0.315	+0.629	<.001	<.001	3	4
BRCA	PDK1 →	-0.719	-0.853	<.001	<.001	3	4
BRCA	RPL3 →	-0.410	-0.778	<.001	<.001	3	4
BRCA	RPS8 →	-0.355	-0.825	<.001	<.001	3	4
BRCA	SEPHS2 →	+0.328	+0.643	<.001	<.001	3	4
OV	SH2B1 →	+0.368	+0.478	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,934 associations by consensus.

ZNF688 vs TTC8 — BRCA

Explore this scatter interactively →