ZNF688

Across TCGA patient cohorts, ZNF688 protein abundance is significantly associated with the RNA expression of many other genes, with 6,303 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible ZNF688-associated genes across cancer lineages are MCM10, TMEM232, and SOX6. Each is linked with ZNF688 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF688-to-partner and partner-to-ZNF688 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF688 versus MCM10 in OV, with a Pearson correlation of -0.82.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF688→partner) and Y-score (partner→ZNF688) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MCM10 →	-2.191	-0.821	<.001	<.001	3	3
UCEC	TMEM232 →	+1.172	+0.353	<.001	<.001	3	3
HNSC	SOX6 →	+0.926	+0.399	<.001	<.001	3	3
HNSC	RIBC1 →	+0.467	+0.307	<.001	<.001	3	3
HNSC	WWOX →	+0.708	+0.432	.001	<.001	3	3
BRCA	RAB32 →	-0.867	-0.738	.003	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,303 associations by consensus.

ZNF688 vs MCM10 — OV

Explore this scatter interactively →