ZNF688

Across TCGA cell cohorts, ZNF688 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,471 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF688-associated GO terms across cancer lineages are Flagellated sperm motility, Cilium-dependent cell motility, and Cilium movement involved in cell motility. Each is linked with ZNF688 in more than 10 cancer types. Because this analysis shows association rather than direction, both ZNF688-to-partner and partner-to-ZNF688 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Flagellated sperm motility grouped by ZNF688-low versus ZNF688-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF688→partner) and Y-score (partner→ZNF688) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Flagellated sperm motility →	-0.111	-0.615	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Cilium-dependent cell motility →	-0.105	-0.647	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Cilium movement involved in cell motility →	-0.109	-0.647	<.001	<.001	3	11
CNS	Regulation of Golgi inheritance →	+0.136	+0.764	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Sperm motility →	-0.111	-0.615	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.105	-0.647	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,471 associations by consensus.

Flagellated sperm motility by ZNF688 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →