ZNF687

Across TCGA pan-cancer cohorts, ZNF687 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ZNF687 data layer compared with 27 for mass-spec protein and 12 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher ZNF687 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated ZNF687 expression acts as an unfavorable survival marker, although some lineages such as LUAD and LSCC show a favorable association.

CCRCC, LUAD, and LSCC are the cancer types where ZNF687 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Median	All	0.699	1.000	.010	8	view →
LUAD	OS	Median	II,III,IV	0.828	0.492	.011	6	view →
LSCC	DFS	Median	II,III,IV	0.821	0.566	.039	3	view →
PDAC	OS	Quartile	All	0.281	0.447	.031	2	view →
GBM	OS	Quartile	All	0.505	0.255	.030	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

ZNF687–CCRCC (OS)

Open the CCRCC breakdown →