ZNF687

Across TCGA patient cohorts, ZNF687 mutation is significantly associated with the RNA expression of many other genes, with 2,890 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF687-associated genes across cancer lineages are LSM3, SNRPA1, and MRPS15. Each is linked with ZNF687 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF687-to-partner and partner-to-ZNF687 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LSM3 grouped by ZNF687-low versus ZNF687-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF687→partner) and Y-score (partner→ZNF687) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LSM3 →	+0.360	+2.042	.004	.004	3	5
BLCA	SNRPA1 →	+0.451	+3.191	.002	.009	2	5
COAD	MRPS15 →	+0.459	+3.713	.001	<.001	3	4
COAD	UBE2F →	+0.334	+3.713	.003	<.001	3	3
BLCA	PSMD12 →	+0.432	+3.606	.007	.001	3	3
BRCA	FGFR3P1 →	+0.081	+4.800	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,890 associations by consensus.

LSM3 by ZNF687 expression — UCEC

Explore this box plot interactively →