ZNF687

Across TCGA cell cohorts, ZNF687 mutation is significantly associated with the RNA expression of many other genes, with 26 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF687-associated genes across cancer lineages are PRSS58, RPL10L, and KRT75. Each is linked with ZNF687 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF687-to-partner and partner-to-ZNF687 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRSS58 grouped by ZNF687-low versus ZNF687-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF687→partner) and Y-score (partner→ZNF687) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	PRSS58 →	+0.092	+5.000	<.001	.006	3	1
BLOOD_Leukemia	RPL10L →	+0.024	+3.874	.004	.005	3	1
BLOOD_Leukemia	KRT75 →	+0.009	+4.037	.001	.004	3	1
BLOOD_Leukemia	MRGPRD →	+0.465	+3.855	.005	.007	3	1
BLOOD_Leukemia	HSD3B1 →	+0.073	+4.133	<.001	.003	3	1
BLOOD_Leukemia	KRTAP10-3 →	+0.037	+4.060	.003	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

PRSS58 by ZNF687 expression — PANCREAS

Explore this box plot interactively →