ZNF687-AS1

Across TCGA pan-cancer cohorts, ZNF687-AS1 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated ZNF687-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher ZNF687-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ZNF687-AS1 expression acts as an unfavorable survival marker, although some lineages such as OV and HNSC show a favorable association.

ACC, OV, and HNSC are the cancer types where ZNF687-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.222	0.662	<.001	124	view →
OV	OS	Tertile	IV	0.798	0.410	<.001	84	view →
HNSC	OS	Tertile	IV	0.787	0.596	.001	45	view →
LGG	OS	Median	All	0.732	0.884	<.001	42	view →
MESO	OS	Tertile	III,IV	0.371	0.640	.004	32	view →
UCEC	OS	Quartile	All	0.511	0.738	.004	26	view →
KIRP	DFS	Median	All	0.874	0.956	.007	21	view →
KIRC	DFS	Quartile	III,IV	0.324	0.568	.011	16	view →
LUAD	DFS	Median	All	0.619	0.735	.013	16	view →
ESCA	DFS	Quartile	III,IV	0.303	0.572	.017	13	view →
COAD	DFS	Median	All	0.388	0.605	.004	13	view →
LAML	DFS	Median	All	0.210	0.546	.006	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

ZNF687-AS1–ACC (DFS)

Open the ACC breakdown →