ZNF684

Across TCGA patient cohorts, ZNF684 protein abundance is significantly associated with the RNA expression of many other genes, with 94 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF684-associated genes across cancer lineages are DUSP6, KIRREL3, and CREG2. Each is linked with ZNF684 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF684-to-partner and partner-to-ZNF684 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF684 versus DUSP6 in UCEC, with a Pearson correlation of 0.97.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF684→partner) and Y-score (partner→ZNF684) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DUSP6 →	+0.710	+0.335	.002	.005	2	1
UCEC	KIRREL3 →	+1.055	+0.335	.008	.005	2	1
UCEC	CREG2 →	+0.770	+0.335	.001	.005	2	1
UCEC	TAFA3 →	+0.215	+0.335	.004	.005	2	1
UCEC	RFX6 →	+0.075	+0.335	.004	.005	2	1
UCEC	RNU6-343P →	+1.139	+0.335	.003	.005	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 94 associations by consensus.

ZNF684 vs DUSP6 — UCEC

Explore this scatter interactively →