ZNF684

Across TCGA cell cohorts, ZNF684 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,979 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF684-associated GO terms across cancer lineages are Mitotic spindle organization, Centrosome cycle, and Microtubule organizing center organization. Each is linked with ZNF684 in more than 14 cancer types. Because this analysis shows association rather than direction, both ZNF684-to-partner and partner-to-ZNF684 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic spindle organization grouped by ZNF684-low versus ZNF684-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF684→partner) and Y-score (partner→ZNF684) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Mitotic spindle organization →	+0.095	+0.619	<.001	<.001	3	15
OVARY	Centrosome cycle →	+0.071	+0.590	.001	<.001	3	15
LUNG_NSCLC_LUSC	Microtubule organizing center organization →	+0.081	+0.800	.003	.002	2	15
KIDNEY	Kinetochore organization →	+0.140	+0.554	<.001	.001	3	14
UPPER_AERODIGESTIVE_TRACT	DNA-templated DNA replication →	+0.096	+0.627	.001	.001	3	14
UPPER_AERODIGESTIVE_TRACT	Regulation of G2/M transition of mitotic cell cycle →	+0.083	+0.588	.003	.004	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,979 associations by consensus.

Mitotic spindle organization by ZNF684 expression — SOFT_TISSUE

Explore this box plot interactively →