ZNF683

Across TCGA patient cohorts, ZNF683 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,212 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF683-associated proteins across cancer lineages are RASAL3, CD8A, and DEF6. Each is linked with ZNF683 in more than 9 cancer types. Because this analysis shows association rather than direction, both ZNF683-to-partner and partner-to-ZNF683 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF683 versus RASAL3 in GBM, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF683→partner) and Y-score (partner→ZNF683) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RASAL3 →	+0.535	+0.424	<.001	<.001	3	10
OV	CD8A →	+0.846	+0.878	<.001	<.001	3	10
UCEC	DEF6 →	+0.506	+0.977	<.001	<.001	3	10
GBM	SASH3 →	+0.591	+0.351	<.001	<.001	3	10
OV	ARHGAP25 →	+1.049	+2.064	.007	.004	3	10
HNSC	ARHGEF6_S225 →	+0.583	+0.772	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,212 associations by consensus.

ZNF683 vs RASAL3 — GBM

Explore this scatter interactively →