ZNF683

Across TCGA patient cohorts, ZNF683 mutation is significantly associated with the RNA expression of many other genes, with 1,037 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF683-associated genes across cancer lineages are LINC01869, RNU6-1301P, and FCGR3A. Each is linked with ZNF683 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF683-to-partner and partner-to-ZNF683 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01869 grouped by ZNF683-low versus ZNF683-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF683→partner) and Y-score (partner→ZNF683) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LINC01869 →	+0.396	+2.439	<.001	.001	3	2
UCEC	RNU6-1301P →	+0.330	+1.730	.002	.003	3	2
UCEC	FCGR3A →	+0.778	+3.700	.004	.001	3	2
UCEC	RNU6-591P →	+0.096	+4.542	<.001	.002	3	2
UCEC	RNU6-649P →	+0.187	+2.242	.001	.005	3	2
UCEC	IGHD3-9 →	+1.244	+2.120	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,037 associations by consensus.

LINC01869 by ZNF683 expression — UCEC

Explore this box plot interactively →