Across TCGA cell cohorts, ZNF682 mutation is significantly associated with the drug of many other genes, with 17 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF682-associated genes across cancer lineages are AZD1208, CZC24832, and 720427. Each is linked with ZNF682 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF682-to-partner and partner-to-ZNF682 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF682→partner) and Y-score (partner→ZNF682) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	AZD1208 →	+0.411	+2.649	.016	.046	3	1
LARGE_INTESTINE	CZC24832 →	+0.275	+2.646	.034	.047	3	1
LARGE_INTESTINE	720427 →	+0.285	+2.649	.031	.046	3	1
LARGE_INTESTINE	JNJ38877605 →	+0.368	+2.786	.034	.037	3	1
LARGE_INTESTINE	615590 →	+0.330	+2.649	.020	.046	2	1
LARGE_INTESTINE	Mirin →	+0.506	+2.646	.006	.047	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

Exploration

ZNF682 survival (RNA) · tumor vs normal (RNA) · all ZNF682 data types