Across TCGA pan-cancer cohorts, ZNF680P1 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of ZNF680P1’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where ZNF680P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ZNF680P1 is over-expressed in tumor, although a few such as THCA and LUSC show the opposite, repressed pattern.

LIHC, THCA, and KIRP are the cancer types where ZNF680P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ZNF680P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	All	All	+0.033	.004	4	view →
THCA	All	II,III,IV	−0.126	.011	3	view →
KIRP	All	All	+0.063	.022	2	view →
LUAD	Male	All	+0.150	.047	1	view →
LUSC	Female	III,IV	−0.065	.005	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: ZNF680P1 RNA expression & survival · all ZNF680P1 data types