ZNF678

Across TCGA patient cohorts, ZNF678 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,418 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF678-associated proteins across cancer lineages are IPO9, GATAD2B, and RO60. Each is linked with ZNF678 in more than 7 cancer types. Because this analysis shows association rather than direction, both ZNF678-to-partner and partner-to-ZNF678 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF678 versus IPO9 in LSCC, with a Pearson correlation of 0.52.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF678→partner) and Y-score (partner→ZNF678) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	IPO9 →	+0.377	+0.641	<.001	<.001	3	8
GBM	GATAD2B →	+0.312	+0.550	<.001	<.001	3	7
UCEC	RO60 →	+0.356	+0.690	<.001	<.001	3	7
LSCC	RPRD2 →	+0.314	+0.628	<.001	<.001	3	7
HNSC	PRCC →	+0.270	+0.881	<.001	<.001	3	6
HNSC	POGZ →	+0.285	+0.676	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,418 associations by consensus.

ZNF678 vs IPO9 — LSCC

Explore this scatter interactively →