ZNF678

Across TCGA patient cohorts, ZNF678 mutation is significantly associated with the RNA expression of many other genes, with 2,447 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF678-associated genes across cancer lineages are SNORA10B, FAF1, and CCND2P1. Each is linked with ZNF678 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF678-to-partner and partner-to-ZNF678 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORA10B grouped by ZNF678-low versus ZNF678-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF678→partner) and Y-score (partner→ZNF678) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	SNORA10B →	+0.304	+5.878	<.001	.002	3	3
UCEC	FAF1 →	+0.289	+2.524	.002	<.001	3	3
BLCA	CCND2P1 →	+0.258	+4.299	<.001	.007	3	2
LIHC	RNA5SP277 →	+0.441	+5.108	<.001	.008	3	2
LIHC	LINC02353 →	+0.065	+5.355	<.001	.005	3	2
LIHC	RNA5SP519 →	+0.345	+6.676	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,447 associations by consensus.

SNORA10B by ZNF678 expression — LIHC

Explore this box plot interactively →