ZNF678

Across TCGA cell cohorts, ZNF678 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible ZNF678-associated genes across cancer lineages are MRAP, IFIT1B, and OR10A5. Each is linked with ZNF678 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF678-to-partner and partner-to-ZNF678 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MRAP grouped by ZNF678-low versus ZNF678-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF678→partner) and Y-score (partner→ZNF678) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	MRAP →	+0.073	+4.807	<.001	.006	3	1
BLOOD_Myeloma	IFIT1B →	+0.013	+4.807	<.001	.006	3	1
STOMACH	OR10A5 →	+0.030	+4.794	<.001	.001	3	1
STOMACH	CYP11B2 →	+0.005	+4.285	<.001	.007	3	1
STOMACH	FSCB →	+0.027	+4.794	<.001	.001	3	1
BLOOD_Lymphoma	TAAR1 →	+0.022	+5.209	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

MRAP by ZNF678 expression — BLOOD_Myeloma

Explore this box plot interactively →