Across TCGA patient cohorts, ZNF677 mutation is significantly associated with the total protein of many other genes, with 37 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF677-associated genes across cancer lineages are p27, TFRC, and ER-alpha_pS118. Each is linked with ZNF677 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF677-to-partner and partner-to-ZNF677 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF677→partner) and Y-score (partner→ZNF677) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p27 →	-0.203	-1.925	.009	.005	3	3
UCEC	TFRC →	+0.513	+1.925	.007	.005	3	3
COAD	ER-alpha_pS118 →	-0.119	-3.161	.033	.019	3	2
UCEC	ER-alpha →	-0.599	-2.222	.043	.010	3	2
COAD	ASNS →	+0.894	+3.178	<.001	.010	3	2
UCEC	ATM →	-0.580	-2.687	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

Exploration

ZNF677 survival (RNA) · tumor vs normal (RNA) · all ZNF677 data types