ZNF675

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF675 mutation is significantly associated with the total protein of many other genes, with 32 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF675-associated genes across cancer lineages are Caspase-7-cleavedD198, Gab2, and STAT3_pY705. Each is linked with ZNF675 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF675-to-partner and partner-to-ZNF675 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF675→partner) and Y-score (partner→ZNF675) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCaspase-7-cleavedD198 →+0.533+2.434.003.00133
UCECGab2 →+0.254+1.201.022.02832
UCECSTAT3_pY705 →-0.378-1.652<.001.00432
UCECATM →-0.427-2.209.002.00932
UCECDi-Ras3 →-0.136-1.893.003<.00132
UCECeIF4E →+0.200+2.662.002<.00122
Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

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