Across TCGA cell cohorts, ZNF675 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,934 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF675-associated GO terms across cancer lineages are DNA damage tolerance, Regulation of chromosome segregation, and Double-strand break repair. Each is linked with ZNF675 in more than 10 cancer types. Because this analysis shows association rather than direction, both ZNF675-to-partner and partner-to-ZNF675 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF675→partner) and Y-score (partner→ZNF675) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	DNA damage tolerance →	+0.061	+0.588	.005	.009	3	11
OVARY	Regulation of chromosome segregation →	+0.107	+1.243	<.001	<.001	3	11
SOFT_TISSUE	Double-strand break repair →	+0.082	+1.298	<.001	<.001	3	11
BLOOD_Lymphoma	Regulation of metaphase/anaphase transition of cell cycle →	+0.106	+1.299	<.001	<.001	3	10
BREAST	Regulation of chromosome organization →	+0.066	+1.332	<.001	<.001	3	10
SOFT_TISSUE	Regulation of sister chromatid segregation →	+0.145	+1.188	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,934 associations by consensus.

Exploration

ZNF675 survival (RNA) · tumor vs normal (RNA) · all ZNF675 data types