Across TCGA cell cohorts, ZNF675 mutation is significantly associated with the RNA expression of many other genes, with 207 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF675-associated genes across cancer lineages are CBY1, ASPN, and TRIM37. Each is linked with ZNF675 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF675-to-partner and partner-to-ZNF675 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF675→partner) and Y-score (partner→ZNF675) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CBY1 →	+0.626	+3.137	.001	.007	3	1
LARGE_INTESTINE	ASPN →	+0.043	+2.600	<.001	.006	3	1
LARGE_INTESTINE	TRIM37 →	+0.599	+3.364	.005	.002	3	1
LARGE_INTESTINE	HINT3 →	+0.645	+3.364	.005	.002	3	1
LARGE_INTESTINE	BAG2 →	+0.907	+3.169	.007	.009	3	1
LARGE_INTESTINE	POLR3G →	+1.229	+3.364	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 207 associations by consensus.

Exploration

ZNF675 survival (RNA) · tumor vs normal (RNA) · all ZNF675 data types