ZNF674

Across TCGA cell cohorts, ZNF674 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,601 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF674-associated GO terms across cancer lineages are Monoubiquitinated protein deubiquitination, Negative regulation of post-translational protein modification, and Golgi to plasma membrane transport. Each is linked with ZNF674 in more than 13 cancer types. Because this analysis shows association rather than direction, both ZNF674-to-partner and partner-to-ZNF674 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Monoubiquitinated protein deubiquitination grouped by ZNF674-low versus ZNF674-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF674→partner) and Y-score (partner→ZNF674) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Monoubiquitinated protein deubiquitination →	+0.109	+0.538	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Negative regulation of post-translational protein modification →	+0.081	+0.596	.004	.005	3	13
SKIN	Golgi to plasma membrane transport →	+0.078	+0.733	<.001	<.001	3	13
LUNG_NSCLC_LUSC	Growth hormone secretion →	+0.127	+0.775	.003	.004	3	12
LUNG_NSCLC_LUSC	Golgi to plasma membrane protein transport →	+0.106	+0.733	.001	.002	3	12
SKIN	Macroautophagy →	+0.055	+0.662	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,601 associations by consensus.

Monoubiquitinated protein deubiquitination by ZNF674 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →