ZNF674

Across TCGA cell cohorts, ZNF674 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZNF674-associated genes across cancer lineages are GAGE12H, ODF4, and SPANXN2. Each is linked with ZNF674 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF674-to-partner and partner-to-ZNF674 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAGE12H grouped by ZNF674-low versus ZNF674-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF674→partner) and Y-score (partner→ZNF674) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	GAGE12H →	+1.799	+5.209	<.001	.005	3	2
BLOOD_Lymphoma	ODF4 →	+0.124	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	SPANXN2 →	+0.199	+5.643	<.001	.002	3	1
BREAST	OR2G6 →	+0.016	+5.169	<.001	.005	3	1
BREAST	VWC2 →	+0.036	+5.169	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

GAGE12H by ZNF674 expression — BLOOD_Lymphoma

Explore this box plot interactively →