ZNF672

Across TCGA pan-cancer cohorts, ZNF672 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ZNF672 data layer compared with 21 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher ZNF672 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated ZNF672 expression acts as an unfavorable survival marker, although some lineages such as UCEC and PDAC show a favorable association.

LSCC, CCRCC, and HNSC are the cancer types where ZNF672 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Median	II,III,IV	0.819	0.988	.020	9	view →
CCRCC	OS	Median	All	0.610	1.000	.028	9	view →
HNSC	OS	Median	III,IV	0.699	0.932	.017	7	view →
UCEC	DFS	Quartile	III,IV	1.000	0.343	.027	4	view →
PDAC	OS	Median	All	1.000	0.799	.030	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

ZNF672–LSCC (DFS)

Open the LSCC breakdown →