ZNF672

Across TCGA pan-cancer cohorts, ZNF672 mass-spec protein differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of ZNF672’s most consistent transcriptional readouts.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where ZNF672 mass-spec protein is repressed in tumor relative to normal tissue. In most cancer types ZNF672 is over-expressed in tumor, although a few such as PDAC and LSCC show the opposite, repressed pattern.

PDAC, LUAD, and LSCC are the cancer types where ZNF672 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ZNF672 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
PDAC	Male	All	−1.010	<.001	7	view →
LUAD	Male	All	+0.306	<.001	7	view →
LSCC	Female	III,IV	−0.497	.014	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

ZNF672–PDAC

Open the PDAC breakdown →