ZNF672

Across TCGA cell cohorts, ZNF672 mutation is significantly associated with the RNA expression of many other genes, with 72 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF672-associated genes across cancer lineages are ISM1, LFNG, and GPR63. Each is linked with ZNF672 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF672-to-partner and partner-to-ZNF672 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ISM1 grouped by ZNF672-low versus ZNF672-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF672→partner) and Y-score (partner→ZNF672) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	ISM1 →	+0.943	+3.417	.009	.004	3	2
BLOOD_Leukemia	LFNG →	-1.147	-3.429	.005	.003	3	1
BLOOD_Leukemia	GPR63 →	+1.007	+3.115	.001	.009	3	1
BLOOD_Leukemia	BNIP1 →	+0.428	+3.260	<.001	.005	3	1
BLOOD_Leukemia	BPHL →	+0.570	+3.489	.005	.001	3	1
BLOOD_Leukemia	NR3C2 →	+0.405	+3.431	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 72 associations by consensus.

ISM1 by ZNF672 expression — BLOOD_Leukemia

Explore this box plot interactively →