ZNF672

Across TCGA cell cohorts, ZNF672 mutation is significantly associated with the mutation status of many other genes, with 4,913 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF672-associated genes across cancer lineages are CDK12, MCM9, and ZC3H3. Each is linked with ZNF672 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF672-to-partner and partner-to-ZNF672 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CDK12 grouped by ZNF672-low versus ZNF672-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF672→partner) and Y-score (partner→ZNF672) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CDK12 →	+3.697	+2.997	<.001	<.001	1	5
BLOOD_Leukemia	MCM9 →	+2.638	+2.341	.009	.009	1	4
BLOOD_Leukemia	ZC3H3 →	+2.638	+2.341	.009	.009	1	4
BLOOD_Leukemia	KCNQ1 →	+3.282	+2.814	<.001	<.001	1	4
OVARY	ERBB3 →	+3.217	+3.684	.006	.006	1	4
BLOOD_Leukemia	GLI2 →	+2.719	+3.918	<.001	<.001	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,913 associations by consensus.

CDK12 by ZNF672 expression — BLOOD_Leukemia

Explore this box plot interactively →