ZNF671

Across TCGA cell cohorts, ZNF671 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,590 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF671-associated GO terms across cancer lineages are Positive regulation of RNA splicing, Protein polyubiquitination, and Primitive hemopoiesis. Each is linked with ZNF671 in more than 8 cancer types. Because this analysis shows association rather than direction, both ZNF671-to-partner and partner-to-ZNF671 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of RNA splicing grouped by ZNF671-low versus ZNF671-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF671→partner) and Y-score (partner→ZNF671) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Positive regulation of RNA splicing →	+0.089	+0.950	<.001	.005	2	9
UPPER_AERODIGESTIVE_TRACT	Protein polyubiquitination →	+0.067	+0.409	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Primitive hemopoiesis →	-0.125	-0.322	.001	.002	3	7
STOMACH	Protein sumoylation →	+0.063	+0.762	.001	.004	3	7
URINARY_TRACT	Centrosome duplication →	+0.086	+0.812	.008	.004	3	6
KIDNEY	Negative regulation of protein ubiquitination →	+0.084	+0.974	.003	.004	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,590 associations by consensus.

Positive regulation of RNA splicing by ZNF671 expression — LIVER

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