ZNF670

Across TCGA patient cohorts, ZNF670 mutation is significantly associated with the total protein of many other genes, with 27 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF670-associated genes across cancer lineages are ATM, Cyclin-B1, and 14-3-3_beta. Each is linked with ZNF670 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF670-to-partner and partner-to-ZNF670 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by ZNF670-low versus ZNF670-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF670→partner) and Y-score (partner→ZNF670) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.391	-2.000	.014	.030	3	2
UCEC	Cyclin-B1 →	+0.516	+2.700	.009	.006	3	2
UCEC	14-3-3_beta →	-0.072	-1.349	.042	.037	3	1
UCEC	EGFR_pY1068 →	-0.266	-2.392	.002	<.001	3	1
UCEC	eIF4E →	+0.158	+1.807	.033	.025	3	1
UCEC	ERK2 →	+0.149	+2.321	.028	.033	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

ATM by ZNF670 expression — UCEC

Explore this box plot interactively →