ZNF670

Across TCGA cell cohorts, ZNF670 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible ZNF670-associated genes across cancer lineages are IFNA16, MS4A6E, and KRTAP4-6. Each is linked with ZNF670 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF670-to-partner and partner-to-ZNF670 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IFNA16 grouped by ZNF670-low versus ZNF670-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF670→partner) and Y-score (partner→ZNF670) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	IFNA16 →	+0.289	+5.029	<.001	.006	3	1
LUNG_SCLC	MS4A6E →	+0.072	+5.029	<.001	.006	3	1
LUNG_SCLC	KRTAP4-6 →	+0.070	+5.643	<.001	.002	3	1
LUNG_SCLC	OR2T5 →	+0.013	+5.643	<.001	.002	3	1
LUNG_NSCLC_LUAD	NKX2-4 →	+0.839	+3.700	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR10AG1 →	+0.025	+4.078	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

IFNA16 by ZNF670 expression — LUNG_SCLC

Explore this box plot interactively →