Across TCGA patient cohorts, ZNF669 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,765 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF669-associated proteins across cancer lineages are GATAD2B, RPRD2, and CDC73. Each is linked with ZNF669 in more than 7 cancer types. Because this analysis shows association rather than direction, both ZNF669-to-partner and partner-to-ZNF669 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF669→partner) and Y-score (partner→ZNF669) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	GATAD2B →	+0.355	+0.818	<.001	<.001	3	8
UCEC	RPRD2 →	+0.291	+0.743	<.001	<.001	3	7
GBM	CDC73 →	+0.310	+0.468	<.001	<.001	3	7
LSCC	CHAMP1 →	+0.355	+0.679	.001	<.001	3	7
HNSC	ARID4B →	+0.305	+0.969	<.001	<.001	3	6
LSCC	HDAC2 →	+0.361	+0.626	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,765 associations by consensus.

Exploration

ZNF669 survival (RNA) · tumor vs normal (RNA) · all ZNF669 data types